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  2. Lysates were analyzed by immunoblotting with anti-EGFR and anti-ОІ-actin antibodies and gels were run under the same experimental conditions. tamoxifen endometrial cancer These results indicate that the growth inhibition synergy and reversal of tamoxifen resistance by combination of selenium with tamoxifen occurs via a tamoxifen-induced cell cycle arrest, allowing more cells to enter the intrinsic apoptotic pathway elicited by selenium.